C143450 Chemical Structure

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25mg
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100mg
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250mg
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C143450

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Product Description

Catalogue NumberC143450
Chemical Name(S)-5-Chloro-N-(3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)thiophene-2-carboxamide
SynonymsRivaroxaban Impurity
CAS Number2204368-63-6
Alternate CAS #366789-02-8
Molecular FormulaC₂₃H₂₁Cl₂N₃O₅S₂
Molecular Weight554.47
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications5-Chloro-N-(3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)thiophene-2-carboxamide is a related compound/ impurity of Rivaroxaban (R538000). Rivaroxaban is a novel antithrombotic agent, a highly potent and selective direct FXa inhibitor.
ReferencesRajan, N., et al.: J. Pharm. Res., 8, 1719 (2014); Ansell, J., et al.: Drugs, 64, 1 (2004); Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005); Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005);