C125000 Chemical Structure

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C125000

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Product Description

Catalogue NumberC125000
Chemical Name(+)-Calanolide A
Synonyms(10R,11S,12S)-11,12-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H,10H-benzo[1,2-b:3,4-b':5,6-b'']tripyran-2-one; [10R-(10α,11β,12α)]-11,12-Dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-2H,6H,10H-benzo[1,2-b:3,4-b':5,6-b'']tripyran-2-one; Calanolide A; NSC 650886
CAS Number142632-32-4
Molecular FormulaC₂₂H₂₆O₅
Molecular Weight370.44
Category Research Tools;
Applications(+)-Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor. It has potent anti-HIV activity.
ReferencesKashman, Y., et al.: J. Med. Chem., 35, 2735 (1992); Jorgensen, W., et al.: Bioorg. Med. Chem. Lett., 16, 663 (2006)