Cabozantinib L-Malate Salt

Catalogue number: C051500
Chemical name: Cabozantinib L-Malate Salt
Synonyms: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N’-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (2S)-2-Hydroxybutanedioic Acid; Cabozantinib S-Malate; XL 184;
CAS Number: 1140909-48-3
Possible CAS #: NA
Molecular form.: C₃₂H₃₀FN₃O₁₀
Appearance: Off-White Solid
Melting Point: 166-169°C
Mol. Weight: 635.59
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.
Dangerous Goods Info: NA
Peer Review Product Citations:
MSDS: C051500.pdf
Keywords: Buy 1140909-48-3 | Purchase 1140909-48-3 | Order 1140909-48-3 | 1140909-48-3 supplier | 1140909-48-3 manufacturer | 1140909-48-3 distributor | 1140909-48-3 cost

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  Pack size Price(USD)
10mg $95.00
250mg $350.00
  Pack size Price(USD)
50mg $225.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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