Catalogue number: C014995
Chemical name: C646
Synonyms: 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid; C 646
CAS Number: 328968-36-1
Possible CAS #: NA
Molecular form.: C₂₄H₁₉N₃O₆
Appearance: Dark Orange Solid
Melting Point: >215°C (dec.)
Mol. Weight: 445.42
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Amines, Apoptosis, Aromatics, Heterocycles, Inhibitors
Boiling Point: No Data Available
Applications: C646 is an inhibitor for histone acetyltransferase p300 and may be a potential candidate for treating AML1-ETO (AE) positive acute myeloid leukemia (AML). It is shown that C646 inhibited cellular proliferation, reduced colony formation, evoked partial cell cycle arrest in the G1 phase, and induced apoptosis in AE-positive AML cell lines and primary blasts isolated from leukemic mice and AML patients.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
Peer Review Product Citations:
Product Reviews:

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  Pack size Price(USD)
1mg $45.00
10mg $225.00
50mg $750.00
  Pack size Price(USD)
5mg $125.00
25mg $450.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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