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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||$ 95.00||0.0|
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|Synonyms||(+)-trans-anti-Benzo[a]pyrene-dG-d8; 10S(+)-trans-anti-[Py]-N2-dG-d8; [7R-(7α,8β,9β,10α)]-2'-deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-d8; Benzo[a]pyrene guanosine deriv.-d8; (+)-r-7,t-8-Dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene-dG-d8; (+)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-d8|
|Alternate CAS #||Unlabelled: 65437-20-9|
|Category||Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites;|
|Applications||Isotope labelled (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts.|
|References||Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Strasser, A. et al.: Cancer Epidemiol. Biomark. Prev., 22, 382 (2013);|