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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 10mg | $ 28045.00 | 0.0 | |
| 25mg | $ 32575.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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B676633
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Product Description
| Catalogue Number | B676633 |
| Chemical Name | (+/-)-trans-anti-N2-BPDE-dG-15N5 |
| Synonyms | [7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-15N5; Benzo[a]pyrene, guanosine deriv.-15N5; (+/-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-15N5 |
| Alternate CAS # | Unlabelled: 85026-87-5 |
| Molecular Formula | C30H2915N5O7 |
| Molecular Weight | 576.55 |
| Category | Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites; |
| Applications | (+/-)-trans-anti-N2-BPDE-dG-15N5 is an isotope labelled analog of (-)-trans-anti-N2-BPDE-dG (B676630), which is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. |
| References | Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Hoare, S. et al.: Biochem., 39, 12252 (2000); Subach, O. et al.: Biochem., 45, 6142 (2006); |