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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
1mg | $ 250.00 | 0.0 | |
5mg | $ 1075.00 | 0.0 | |
10mg | $ 2035.00 | 0.0 | |
Exact Weight Packaging | $ 75.00 | 0.0 | |
Total | $ 0.0 |
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B676630
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Product Description
Catalogue Number | B676630 |
Chemical Name | (-)-trans-anti-N2-BPDE-dG |
Synonyms | [7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine; Benzo[a]pyrene, guanosine deriv.; (-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene |
CAS Number | 85026-87-5 |
Molecular Formula | C₃₀H₂₇N₅O₇ |
Molecular Weight | 569.56 |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; Environmental Standards, Mutagens and Metabolites; |
Applications | (-)-trans-anti-N2-BPDE-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. |
References | Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Hoare, S. et al.: Biochem., 39, 12252 (2000); Subach, O. et al.: Biochem., 45, 6142 (2006); |