(1R,2R)-Bortezomib

Catalogue number: B675705
Chemical name: (1R,2R)-Bortezomib
Synonyms: B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid;
CAS Number: 1132709-15-9
Possible CAS #: NA
Molecular form.: C₁₉H₂₅BN₄O₄
Appearance: White Solid
Melting Point: >167ºC (dec.)
Mol. Weight: 384.24
Storage: -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $140.00
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  Pack size Price(USD)
50mg $1120.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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