Catalogue number: B656650
Chemical name: (S)-1-Boc-3-hydroxypiperidine
Synonyms: (3S)-3-Hydroxy-1-piperidinecarboxylic Acid 1,1-dimethylethyl Ester; (S)-3-Hydroxypiperidine-1-carboxylic Acid tert-Butyl Ester; (S)-N-Boc-3-hydroxypiperidine; (S)-tert-Butyl 3-Hydroxypiperidine-1-carboxylate; 1,1-Dimethylethyl (3S)-3-Hydroxy-1-piperidinecarboxylate; 1-Boc-(3S)-3-hydroxypiperidine; tert-Butyl (S)-3-Hydroxypiperidine-1-carboxylate; (S)-N-Boc-3-hydroxypiperidine;
CAS Number: 143900-44-1
Possible CAS #: NA
Molecular form.: C₁₀H₁₉NO₃
Appearance: White to Pale Yellow Low Melting Solid
Melting Point: 38-41°C
Mol. Weight: 201.26
Storage: Refrigerator
Solubility: Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Ethyl Acetate (Sligh
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: (S)-1-Boc-3-hydroxypiperidine is an important chiral intermediate for the synthesis of ibrutinib, an anticancer drug targeting B-cell malignancies. Synthesis of pharmaceutical intermediates including ibrutinib, the API of the newly approved drug Imbruvica, for the treatment of lymphoma.
Dangerous Goods Info: NA
Peer Review Product Citations:
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