B415295 Chemical Structure

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Product Description

Catalogue NumberB415295
Chemical NameN2,N6-Bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-L-lysinamide
SynonymsCTCE 9908
CAS Number1030384-98-5
Molecular FormulaC86H147N27O23
Molecular Weight1927.25
Category Research Tools;
ApplicationsCXCR4 is a chemokine receptor often overexpressed in cancer cells and involved with metastasis. N2,N6-Bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-L-lysinamide is a CXCR4 antagonist. It inhibits ovarian cancer cell migration to CXCL12 and induces cell death in CXCR4-positive cells.
ReferencesKwong, J., et al.: Mol Cancer Ther. 8, 1893 (2009); Hassan, S., et al.: Int J Cancer. 129, 225 (2011)