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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
1mg | $ 250.00 | 0.0 | |
Exact Weight Packaging | $ 145.00 | 0.0 | |
Total | $ 0.0 |
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B415295
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Product Description
Catalogue Number | B415295 |
Chemical Name | N2,N6-Bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-L-lysinamide |
Synonyms | CTCE 9908 |
CAS Number | 1030384-98-5 |
Molecular Formula | C86H147N27O23 |
Molecular Weight | 1927.25 |
Category | Research Tools; |
Applications | CXCR4 is a chemokine receptor often overexpressed in cancer cells and involved with metastasis. N2,N6-Bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-L-lysinamide is a CXCR4 antagonist. It inhibits ovarian cancer cell migration to CXCL12 and induces cell death in CXCR4-positive cells. |
References | Kwong, J., et al.: Mol Cancer Ther. 8, 1893 (2009); Hassan, S., et al.: Int J Cancer. 129, 225 (2011) |