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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
2.5mg | $ 195.00 | 0.0 | |
25mg | $ 1540.00 | 0.0 | |
Exact Weight Packaging | $ 95.00 | 0.0 | |
Total | $ 0.0 |
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B330251
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Product Description
Catalogue Number | B330251 |
Chemical Name | 3-epi-Betulinic Acid-d3 |
Synonyms | 3-epi-Mairin-d3; 3-epi-Betulic Acid-d3; 3-epi-Lupatic Acid-d3; 3-epi-NSC 113090-d3; |
Alternate CAS # | Unlabelled: 472-15-1 |
Molecular Formula | C₃₀H₄₅D₃O₃ |
Appearance | White Solid |
Molecular Weight | 459.72 |
Solubility | DMSO, Ethyl Acetate, Methanol |
Category | Standards; Steroids; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | 3-epi-Betulinic Acid-d3 is an isotope labelled analog of Betulinic Acid (B330250); a natural pentacyclic triterpenoid that displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity. In addition, 3-epi-Betulinic Acid-d3 is an epimer by-product isomer of Betulinic Acid-d3 (B330252). |
References | Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010) |