B330251 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
2.5mg
$ 195.000.0
25mg
$ 1540.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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B330251

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Product Description

Catalogue NumberB330251
Chemical Name3-epi-Betulinic Acid-d3
Synonyms3-epi-Mairin-d3; 3-epi-Betulic Acid-d3; 3-epi-Lupatic Acid-d3; 3-epi-NSC 113090-d3;
Alternate CAS #Unlabelled: 472-15-1
Molecular FormulaC₃₀H₄₅D₃O₃
AppearanceWhite Solid
Molecular Weight459.72
SolubilityDMSO, Ethyl Acetate, Methanol
Category Standards; Steroids; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications3-epi-Betulinic Acid-d3 is an isotope labelled analog of Betulinic Acid (B330250); a natural pentacyclic triterpenoid that displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity. In addition, 3-epi-Betulinic Acid-d3 is an epimer by-product isomer of Betulinic Acid-d3 (B330252).
ReferencesPisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010)