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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1g | $ 110.00 | 0.0 | |
| 5g | $ 180.00 | 0.0 | |
| 25g | $ 425.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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B330240
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Product Description
| Catalogue Number | B330240 |
| Chemical Name | Betulin |
| Synonyms | Lup-20(29)-ene-3β,28-diol; Lup-20(30)-ene-3β,28-diol; 3aH-Cyclopenta[a]chrysene, lup-20(29)-ene-3,28-diol deriv.; (+)-Betulin; 3,28-Dihydroxy-lupeol; 3β,28-Dihydroxylup-20(29)-ene; Betulin; Betuline; Betulinic alcohol; Betulinol; Betulol; NSC 4644; Trochol |
| CAS Number | 473-98-3 |
| Molecular Formula | C₃₀H₅₀O₂ |
| Appearance | Pale Brown to Beige Solid |
| Melting Point | >250°C (dec.) |
| Molecular Weight | 442.72 |
| Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| Stability | Hygroscopic |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Betulin is a derivative of Betulinic Acid (B330250), used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity |
| References | Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010); |