All Products are stable to be shipped at room temperature, unless otherwise specified.
|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||$ 145.00||0.0|
Product successfully added to cart.
- Request another packsize ? Click here.
- Inventory Status : Pending QC
- Ships On :
Bulk Order Request for B285725
|Synonyms||GSK-3ß Inhibitor I, TDZD-8|
|Category||Research Tools; Enzyme Activators and Inhibitors;|
|Applications||Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3ß ( IC50 =2nM). Binds to the active site of GSK-3ß. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).|
|References||Martinez, A., et al.: J. Med. Chem., 45, 1292 (2002)|