Catalogue number: B285725
Chemical name: 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Synonyms: GSK-3ß Inhibitor I, TDZD-8
CAS Number: 327036-89-5
Alternate CAS #: NA
Molecular form.: C₁₀H₁₀N₂O₂S
Appearance: White Solid
Melting Point: 60-61°C
Mol. Weight: 222.26
Storage: -20°C Freezer
Solubility: Hexane
Stability: No Data Available
Category: Amines, Aromatics, Inhibitors, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3ß ( IC50 =2nM). Binds to the active site of GSK-3ß. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
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  Pack size Price(USD)
1mg $50.00
10mg $60.00
50mg $150.00
  Pack size Price(USD)
5mg $55.00
25mg $90.00
100mg $250.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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