B119530 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
10mg
$ 213.000.0
25mg
$ 488.000.0
50mg
$ 953.000.0
100mg
$ 1631.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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B119530

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Product Description

Catalogue NumberB119530
Chemical Name(aS,bS)-rel-Bedaquiline
Synonyms(1S,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol
Molecular FormulaC₃₂H₃₁BrN₂O₂
Molecular Weight555.5
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(aS,bS)-rel-Bedaquiline is an intermediate in the synthesis of (aS,bR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
ReferencesCheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);