BAY 87-2243-d8


Catalogue Number: B119072
Chemical Name: BAY 87-2243-d8
Synonyms: 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]-piperazine-d8
Alternate CAS #: Unlabelled: 1227158-85-1
Molecular Formula: C₂₆H₁₈D₈F₃N₇O₂
Molecular Weight: 533.57
Applications: Isotope labelled BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation. It is found to inhibit HIF-1α and HIF-2α protein accumulation under hypoxic conditions in non-small cell lung cancer cell line H460. It inhibits mitochondrial complex I activity and therefore may be used in antitumor treatment to overcome chemo- and radiotherapy- resistance of hypoxic tumors.
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All Products are stable to be shipped at room temperature, unless otherwise specified.
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0.5mg $250.00
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5mg $2075.00
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10mg $1275.00
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