A965309 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 45.000.0
5mg
$ 130.000.0
10mg
$ 200.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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  • Ships On : 5/23/2022
A965309

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Product Description

Catalogue NumberA965309
Chemical NameAZD-5069
SynonymsN-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-4-pyrimidinyl]-1-azetidinesulfonamide; N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[((1R,2S)-2,3-dihydroxy-1-methylpropyl)oxy]-4-pyrimidinyl]-1-azetidinesulfonamide; N-(2-((2,3-Difluorobenzyl)thio)-6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide
CAS Number878385-84-3
Molecular FormulaC₁₈H₂₂F₂N₄O₅S₂
AppearanceWhite to Off-White Solid
Melting Point149-152°C
Molecular Weight476.52
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAZD-5069 is a potent and selective CXCR2 antagonist with potential as a therapeutic agent in inflammatory conditions.
ReferencesDe S., et al.: Eur. Respir. J., 46, 1021 (2015); Jurcevic, S., et al.: Br. J. Clin. Pharmacol., 80, 1324 (2015); Nicholls, D. J., et al.: J. Pharmacol. Exp. Ther., 353, 340 (2015)