A787035 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
0.25mg
$ 195.000.0
0.5mg
$ 375.000.0
1mg
$ 705.000.0
2.5mg
$ 1640.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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A787035

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Product Description

Catalogue NumberA787035
Chemical Name(-)-Ascofuranone
Synonyms3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3-methyl-7-[(2S)-tetrahydro-5,5-dimethyl-4-oxo-2-furanyl]-2,6-octadien-1-yl]benzaldehyde; [S-(E,E)]-3-Chloro-4,6-dihydroxy-2-methyl-5-[3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxo-2-furanyl)-2,6-octadienyl]-benzaldehyde; Ascofuranone;
CAS Number38462-04-3
Molecular FormulaC₂₃H₂₉ClO₅
Molecular Weight420.93
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications(-)-Ascofuranone is an antibiotic with antitumor activity. It suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. (-)-Ascofuranone was effective in the treatment against Trypanosoma brucei brucei infection in mice.
ReferencesYabu, Y., et al.: Parasitol. Int., 52, 155 (2003); Cho, H., et al.: Carcinogenesis, 28, 1104 (2007);