Aprepitant-d4

Catalogue number: A729803
Chemical name: Aprepitant-d4
Synonyms: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend-d4; L 754030-d4; MK 0869-d4; MK 869-d4; ONO 7436-d4;
Impurity:
CAS Number: 1133387-60-6
Possible CAS #: NA
Molecular form.: C₂₃H₁₇D₄F₇N₄O₃
Appearance: White Solid
Melting Point: 242-244°C
Mol. Weight: 538.45
Storage: -20°C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
MSDS: A729803.pdf
Keywords: Buy 1133387-60-6 | Purchase 1133387-60-6 | Order 1133387-60-6 | 1133387-60-6 supplier | 1133387-60-6 manufacturer | 1133387-60-6 distributor | 1133387-60-6 cost

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  Pack size Price(USD)
1mg $175.00
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  Pack size Price(USD)
10mg $1400.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock



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