Catalogue number: A729800
Chemical name: Aprepitant
Synonyms: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030; MK 0869; MK 869; ONO 7436;
CAS Number: 170729-80-3
Possible CAS #: NA
Molecular form.: C₂₃H₂₁F₇N₄O₃
Appearance: White to Pale Beige Solid
Melting Point: 242-250°C
Mol. Weight: 534.43
Storage: -20°C Freezer
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Aprepitant is a neurokinin-1 antagonist and an antiemetic agent (1). It is used to prevent chemotherapy-induced nausea and vomiting (CINV) in colorectal cancer patients (2) Aprepitant has also been shown to induce apoptotic cell death and G1 arrest through Akt/p53 axis in pre-B acute lymphoblastic leukemia cells (3).
Dangerous Goods Info: NA
References: PMID: 27465476
PMID: 27609608
PMID: 15485308
Peer Review Product Citations:
MSDS: A729800.pdf

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  Pack size Price(USD)
1mg $60.00
10mg $95.00
100mg $250.00
  Pack size Price(USD)
5mg $70.00
25mg $150.00
250mg $425.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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