Catalogue number: A726300
Chemical name: Apicidin
Synonyms: Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]; Cyclo(8-oxo-L-2-aminodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl- D-2-piperidinecarbonyl); Apicidin Ia; OSI 2040;
CAS Number: 183506-66-3
Possible CAS #: NA
Molecular form.: C₃₄H₄₉N₅O₆
Appearance: White Solid
Melting Point: 188-190ºC
Mol. Weight: 623.78
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Apicidin is a potent (nM) cell permeable inhibitor of histone deacetylase. Also, Apicidin exhibits antiprotozoal and potential antimalarial properties. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
2.5mg $190.00
  Pack size Price(USD)
25mg $1520.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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