Apatinib

Catalogue number: A726150
Chemical name: Apatinib
Synonyms: N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide; YN968D1 ;
Impurity:
CAS Number: 811803-05-1
Possible CAS #: NA
Molecular form.: C₂₄H₂₃N₅O
Appearance: Pale Yellow to Yellow Solid
Melting Point: 111-114°C
Mol. Weight: 397.47
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Very Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:
MSDS: A726150.pdf

Order Product

  Pack size Price(USD)
10mg $150.00
?
100mg $1195.00
?
  Pack size Price(USD)
50mg $700.00
?


Exact Weight Packaging ($75(USD) / Vial)
?
Inventory Status:   In Stock



Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:
Translate »