A637200 Chemical Structure

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25mg
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A637200

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Product Description

Catalogue NumberA637200
Chemical NameAnacetrapib
Synonyms(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-2-oxazolidinone; (4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one; MK 0859
CAS Number875446-37-0
Molecular FormulaC₃₀H₂₅F₁₀NO₃
Molecular Weight637.51
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAn orally active and potent cholesterol ester transfer protein (CETP) inhibitor for the treatment of atherosclerosis, in particular dyslipidemia.
ReferencesKrishna, R. et al.: Br. J. Clin. Pharmacol., 67, 520 (2009); Vergeer, M. et al.: Nat. Clin. Pract. Cardiovasc. Med., 5, 302 (2008); Masson, D.: Curr. Opin. Invest. Drugs, 10, 980 (2009);