A622260 Chemical Structure

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A622260

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Product Description

Catalogue NumberA622260
Chemical Name[6R-[6α,7β(R*)]]-7-[(Aminophenylacetyl)amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid
SynonymsIsocefalexine; Cefaclor Impurity G (EP)
CAS Number67308-21-8
Alternate CAS #Sodium Salt: 37050-97-8
Molecular FormulaC₁₆H₁₇N₃O₄S
AppearanceWhite to Pale Beige Solid
Melting Point166-169ºC
Molecular Weight347.39
StorageAmber Vial, -20°C Freezer, Under inert atmosphere
SolubilityDMSO (Slightly, Heated), Methanol (Slightly), Water (Very Slightly, Heated)
StabilityLight Sensitive
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications[6R-[6α,7β(R*)]]-7-[(Aminophenylacetyl)amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid is an impurity of Cefaclor (C235250), an second-generation cephalosporin antibiotic for antibacterial purposes.
ReferencesGray, B.M., et al.: Antimicrob. Agents Chemother., 13, 988 (1978), Lorenz, L.J., et al.: Anal. Profiles Drug Subs., 9, 107 (1980), Hori, R., et al.: J. Pharm. Pharmacol., 40, 646 (1988),