Catalogue Number: A621350
Chemical Name: 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline
Synonyms: N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine; QNZ;
CAS Number: 545380-34-5
Molecular Formula: C₂₂H₂₀N₄O
Appearance: Off-White to Brownish-Yellow Solid
Melting Point: >170°C (dec.)
Molecular Weight: 356.42
Storage: Refrigerator, Under Inert Atmosphere
Solubility: DMSO, Methanol (Sparingly)
Category: Amines, Aromatics, Heterocycles, Inhibitors
Applications: QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1mg/Kg). A useful tool to explore the role of NFkB in cellular signaling pathways.

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: A621350.pdf
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  Pack size Price(USD)
500µg $50.00
2mg $65.00
10mg $140.00
  Pack size Price(USD)
1mg $55.00
5mg $85.00
25mg $360.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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