A618895 Chemical Structure

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A618895

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Product Description

Catalogue NumberA618895
Chemical Name(+)-6-Aminopenicillanic Acid
Synonyms(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; 6-APA; 6-APS; 6β-Aminopenicillanic acid; NSC 50071; [2S-(2α,5α,6β)]-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; 6-Aminopenicillinate; USP Amoxicillin Related Compound A, Sulbactam Impurity B EP, Amoxicillin EP Impurity A
ImpurityAmpicillin EP Impurity A ; Amoxicillin USP Related Compound A
CAS Number551-16-6
Molecular FormulaC₈H₁₂N₂O₃S
AppearanceWhite Solid
Melting Point>180ºC (dec.)
Molecular Weight216.26
StorageAmber Vial, -20°C Freezer
SolubilityAqueous Acid (Slightly), Methanol (Slightly), Water (Slightly, Heated)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(+)-6-Aminopenicillanic Acid (Amoxicillin EP Impurity A) is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
ReferencesZel'tser, I.Z. et al.: Gig. Truda Prof. Zabol., 5, 59 (1983); Hamilton-Miller, J.M.T.: Int. J. Antimicrob. Agents, 31, 189 (2008); Novikova, N.D. et al.: Mikol. Fitopatol., 7, 101 (1973);