A614410 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 50.000.0
5mg
$ 105.000.0
10mg
$ 170.000.0
50mg
$ 675.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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  • Ships On : 5/23/2022
A614410

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Product Description

Catalogue NumberA614410
Chemical NameAMG 837
Synonyms(βS)-β-1-Propynyl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-benzenepropanoic Acid; (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic Acid;
CAS Number865231-46-5
Molecular FormulaC₂₆H₂₁F₃O₃
Molecular Weight438.44
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity.
ReferencesDragano, N. R. V., et al.: J Neuroinflammation. 14, 91 (2017); Houze, J. B., et al.: Bioorg Med Chem Lett. 22, 1267 (2012)