A612495 Chemical Structure

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1mg
$ 170.000.0
10mg
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A612495

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Product Description

Catalogue NumberA612495
Chemical Name((2R,3S,5S)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl 4-chlorobenzoate
Molecular FormulaC₁₅H₁₅ClN₄O₅
Molecular Weight366.76
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications((2R,3S,5S)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl 4-chlorobenzoate is an impurity of Decitabine (D226730), shown to inhibit DNA methylation resulting in an effective anticancer agent.
ReferencesHajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);