A604435 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
2.5mg
$ 180.000.0
5mg
$ 330.000.0
mg10
$ 630.000.0
25mg
$ 1390.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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A604435

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Product Description

Catalogue NumberA604435
Chemical Name(Z)-7-(((R)-2-Amino-2-carboxyethyl)thio)-2-(2,3-dimethylbut-3-enamido)hept-2-enoic Acid
SynonymsCliastatin Impurity F;
ImpurityCliastatin Impurity F;
Molecular FormulaC16H26N2O5S
AppearanceOff-White Solid
Melting Point>143°C (dec.)
Molecular Weight358.45
StorageAmber Vial, -20°C Freezer, Under inert atmosphere
SolubilityMethanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(Z)-7-(((R)-2-Amino-2-carboxyethyl)thio)-2-(2,3-dimethylbut-3-enamido)hept-2-enoic Acid is an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
ReferencesFinlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),