Aloisine A RP107

Catalogue number: A575450
Chemical name: Aloisine A RP107
Synonyms: RP107, 7-n-Butyl-6-(4-hydroxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine; 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol;
CAS Number: 496864-16-5
Alternate CAS #: NA
Molecular form.: C₁₆H₁₇N₃O
Appearance: Light Orangish Yellow solid
Melting Point: 151-153°C (dec.)
Mol. Weight: 267.33
Storage: -20˚C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Protein Kinase Inhibitors and Activators
Boiling Point: No Data Available
Applications: A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of cyclin dependent kinases (Cdks: IC50 =150nM, 120 nM, 400 nM and 200 nM for Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk5/p25, respectively). Also inhibits the activity of clycogen synthase kinase-3 (GSK-3,:(IC50 =500 nM and 1.5 uM for GSK-3a, GSK-3ß, respectively), and c-Jun N-terminal kinase (JNK: IC50 approx. 3-10uM).
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: A575450.pdf
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  Pack size Price(USD)
5mg $110.00
25mg $405.00
100mg $1185.00
  Pack size Price(USD)
10mg $150.00
50mg $800.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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