A450250 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 180.000.0
5mg
$ 870.000.0
10mg
$ 1735.000.0
25mg
$ 4330.000.0
100mg
$ 17305.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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A450250

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Product Description

Catalogue NumberA450250
Chemical NameAklavine
Synonyms(1R,2R,4S)-2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-1-naphthacenecarboxylic Acid Methyl Ester; 1-Deoxypyrromycin; Aclacinomycin T; Aklavin; Antibiotic MA 144T1; MA 144T1; (1R,2R,4S)-Methyl 2-Ethyl-2,5,7-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate;
CAS Number60504-57-6
Molecular FormulaC₃₀H₃₅NO₁₀
Molecular Weight569.6
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; Environmental Standards, Mutagens and Metabolites;
ApplicationsAklavine is an anthracycline based anticancer antibiotic, in which it is biosynthesized by S-Adenosyl-l-methionine (SAM)-dependent Methyltransferases.
ReferencesGrocholski, T., et al.: Proc. Natl. Acad. Sci. U. S. A., 112, 9866 (2015)