A357460 Chemical Structure

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  • Ships On : 4/13/2023

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Product Description

Catalogue NumberA357460
Chemical NameAflatoxin B1
Synonyms(6aR,9aS)-2,3,6a,9a-Tetrahydro-4-methoxy-1H,11H-cyclopenta[c]furo[3’,2’:4,5]furo[2,3-h][1]benzopyran-1,11-dione; (-)-Aflatoxin B1; AFB1; NSC 529592;
CAS Number1162-65-8
Molecular FormulaC₁₇H₁₂O₆
AppearanceWhite to Very Dark Brown Solid
Melting Point>182°C (dec.)
Molecular Weight312.27
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Controlled Substances and Drugs of Abuse for Forensic Testing;
ApplicationsAflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Aflatoxin is biotransformed to genotoxic intermediates by P450 Phase I enzymes, mainly CYP3A4 via aflatoxin B1 3-hydroxylation. Detoxification depends on Phase II enzymes, such as Glutathione S-Transferase and AFB(1)-aldehyde reductase (AFAR).Aflatoxin B1 is one of the most potent environmental mutagens and carcinogens known.Environmental contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesCifford, R., et al.: Nature, 209, 312 (1966); Wogan, et al.: Food Cosmet. Toxicol., 12, 681 (1974); Sinz, M.W., et al.: J. Toxicol. Toxin Rev., 10, 87 (1991);