(-)-Actinonin


Catalogue number: A192000
Chemical name: (-)-Actinonin
Synonyms: (2R)-N4-Hydroxy-N1-[(1S)-1-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentyl-butanediamide; Actinonine; 3-[[1-[[2-(Hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic Acid; Actinonin; CONA 57; Ro 06-1467;
Impurity:
CAS Number: 13434-13-4
Possible CAS #: NA
Molecular form.: C₁₉H₃₅N₃O₅
Appearance: Off-White to Light Beige Solid
Melting Point: 137-139°C
Mol. Weight: 385.5
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Chiral Reagents, Inhibitors, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (-)-Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of aminopeptidase M and leucine aminopeptidase. Actinonin has observed to be an inhibitor of peptide deformylase, meprin A, and thermolysin. Actinonin also inhibits tumor cell invasion and matrix degradation along with displayed antitumor activity in vitro and in vivo as well as acting as an apoptotic inducer.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
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10mg $350.00
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