A187520 Chemical Structure

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A187520

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Product Description

Catalogue NumberA187520
Chemical NameO-Acetyl Psilocin Fumarate
Synonyms3-[2-(Dimethylamino)ethyl]-1H-indol-4-ol 4-Acetate Fumarate;
CAS Number1217230-42-6
Alternate CAS #92292-84-7-free base
Molecular FormulaC₁₈H₂₂N₂O₆
AppearanceDark Green-Grey Solid
Melting Point170-176°C (dec.)
Molecular Weight362.38
StorageHygroscopic, Refrigerator, Under Inert Atmosphere
SolubilityMethanol, Water
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsIt is readily crystallized as the fumarate salt, and is considerably more stable than Psilocin (P839630) itself. It would seem to be an ideal prodrug to replace Psilocybin in future clinical studies, since Psilocin is the principal metabolite of Psilocibin. Controlled substance (hallucinogen).
ReferencesMigliaccio, G., et al.: J. Med. Chem., 24, 206 (1981), Strassman, R., et al.: Arch. Gen. Psych., 51, 85 (1994), Hasler, F., et al.: Pharm. Acta Helv., 72, 175 (1997),