A158340 Chemical Structure

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500mg
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1000mg
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5g
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A158340

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Product Description

Catalogue NumberA158340
Chemical Nametrans-4-Acetamidocyclohexanol
Synonymstrans-N-(4-Hydroxycyclohexyl)-acetamide;
CAS Number27489-60-7
Molecular FormulaC₈H₁₅NO₂
AppearanceWhite to Off-White Solid
Melting Point127 - 144°C
Molecular Weight157.21
Storage-20°C, Inert atmosphere
SolubilityDichloromethane (Slightly, Heated), DMSO (Slightly), Methanol (Slightly), Water
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applicationstrans-4-Acetamidocyclohexanol is an intermediate in the synthesis of 4”-trans-Hydroxy Cilostazol (H918300), a metabolite of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
Referencesde Morais, S., et al.: J. Biol. Chem., 269, 15419 (1994); Tata, P; J Pharm Biomed Anal, 24, 381