A144905 Chemical Structure

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10mg
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A144905

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Product Description

Catalogue NumberA144905
Chemical Name(S)-N-(Acetamido-2-hydroxypropyl)-N-(3-fluoro-4-morpholinophenyl)acetamide
Molecular FormulaC₁₇H₂₄FN₃O₄
AppearanceWhite to Off-White Solid
Melting Point>42°C (dec.)
Molecular Weight353.39
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityChloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
StabilityHygroscopic
Category Building Blocks; Chiral Molecules;
Applications(S)-N-(Acetamido-2-hydroxypropyl)-N-(3-fluoro-4-morpholinophenyl)acetamide is an impurity of Linezolid (L466500), a prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.
ReferencesBrickner, S.J., et al.: J. Med. Chem., 39, 673 (1996), Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996), Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998), Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002),