Acalabrutinib
| Catalogue number: | A115605 |
| Chemical name: | Acalabrutinib |
| Synonyms: | 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide; ACP 196 |
| Impurity: | |
| CAS Number: | 1420477-60-6 |
| Possible CAS #: | NA |
| Molecular form.: | C₂₆H₂₃N₇O₂ |
| Appearance: | No Data Available |
| Melting Point: | No Data Available |
| Mol. Weight: | 465.51 |
| Storage: | No Data Available |
| Solubility: | No Data Available |
| Stability: | No Data Available |
| Category: | No Data Available |
| Boiling Point: | No Data Available |
| Applications: | Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton’s tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL). |
| Dangerous Goods Info: | NA |
| References: | |
| Peer Review Product Citations: | |
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