A115153 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
5mg
$ 55.000.0
10mg
$ 65.000.0
50mg
$ 105.000.0
100mg
$ 195.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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A115153

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Product Description

Catalogue NumberA115153
Chemical NameAbemaciclib
SynonymsN-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY 2835219; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine
CAS Number1231929-97-7
Molecular FormulaC₂₇H₃₂F₂N₈
AppearancePale Yellow to Light Yellow Solid
Melting Point175 - 178°C
Molecular Weight506.59
Storage-20°C
SolubilityChloroform (Slightly), Methanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors;
ApplicationsAbemaciclib is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesO'Leary, Ben., et al.: Nat Rev Clin Oncol.,  13, 417 (2016); Van Arsdale., et al.: Clin. Cancer Res., 21, 2905 (2015);