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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 10mg | $ 75.00 | 0.0 | |
| 50mg | $ 121.00 | 0.0 | |
| 100mg | $ 224.00 | 0.0 | |
| Exact Weight Packaging | $ 145.00 | 0.0 | |
| Total | $ 0.0 | ||
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A115153
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Product Description
| Catalogue Number | A115153 |
| Chemical Name | Abemaciclib |
| Synonyms | N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY 2835219; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine |
| CAS Number | 1231929-97-7 |
| Molecular Formula | C₂₇H₃₂F₂N₈ |
| Appearance | Pale Yellow to Light Yellow Solid |
| Melting Point | 175 - 178°C |
| Molecular Weight | 506.59 |
| Storage | -20°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; |
| Applications | Abemaciclib is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells. |
| Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package | |
| References | O'Leary, Ben., et al.: Nat Rev Clin Oncol., 13, 417 (2016); Van Arsdale., et al.: Clin. Cancer Res., 21, 2905 (2015); |