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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 65.00 | 0.0 | |
| 10mg | $ 75.00 | 0.0 | |
| 25mg | $ 110.00 | 0.0 | |
| 50mg | $ 178.00 | 0.0 | |
| 100mg | $ 247.00 | 0.0 | |
| 250mg | $ 391.00 | 0.0 | |
| Exact Weight Packaging | $ 145.00 | 0.0 | |
| Total | $ 0.0 | ||
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A112580
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Product Description
| Catalogue Number | A112580 |
| Chemical Name | ABT 888 |
| Synonyms | 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide; A 861695; |
| CAS Number | 912444-00-9 |
| Molecular Formula | C₁₃H₁₆N₄O |
| Appearance | Off-White to Dark Yellow Solid |
| Melting Point | >173°C (dec.) |
| Molecular Weight | 244.29 |
| Storage | 4°C |
| Solubility | Methanol (Slightly), THF (Slightly) |
| Category | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Potent PARP inhibitor. |
| References | Virag, L., et al.: Pharmacol. Rev., 54, 375 |