All Products are stable to be shipped at room temperature, unless otherwise specified.
| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1mg | $ 190.00 | 0.0 | |
| 10mg | $ 1487.00 | 0.0 | |
| Exact Weight Packaging | $ 145.00 | 0.0 | |
| Total | $ 0.0 | ||
Product successfully added to cart.
- Request another packsize ? Click here.
- Inventory Status : Currently Back Ordered - Please Request Lead Time
- Ships On :
A112552
Bulk Order Request for A112552
Product Description
| Catalogue Number | A112552 |
| Chemical Name | ABT 737-d8 |
| Synonyms | 4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide-d8; |
| CAS Number | 1217686-68-4 |
| Molecular Formula | C₄₂H₃₇D₈ClN₆O₅S₂ |
| Appearance | Yellow Solid |
| Melting Point | 148-150˚C |
| Molecular Weight | 821.48 |
| Storage | -20°C |
| Solubility | DMSO |
| Category | Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | A selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines. |
| References | Ikegaki, N., et al.: Cancer Res., 54, 6 (1994), Kaiser, U., et al.: Lung Cancer, 15, 31 (1996), Rudin, C., et al.: J. Clin. Oncol., 22, 1110 ( 2004), Konopleva, M., et al.: Cancer Cell, 10, 375 (2006), Trudel, S., et al.: Clin. Cancer Res., 13, 621 (2007), |