A112550 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 55.000.0
5mg
$ 85.000.0
10mg
$ 140.000.0
25mg
$ 260.000.0
50mg
$ 330.000.0
100mg
$ 630.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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A112550

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Product Description

Catalogue NumberA112550
Chemical NameABT 737
Synonyms4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide;
CAS Number852808-04-9
Molecular FormulaC₄₂H₄₅ClN₆O₅S₂
AppearanceLight Yellow to Yellow Solid
Melting Point134-138°C (dec.)
Molecular Weight813.43
Storage-20°C
SolubilityDMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Category Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines. Potent Bcl-2 Family inhibitor.
ReferencesIkegaki, N., et al.: Cancer Res., 54, 6