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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
1mg | $ 63.00 | 0.0 | |
5mg | $ 97.00 | 0.0 | |
10mg | $ 159.00 | 0.0 | |
25mg | $ 295.00 | 0.0 | |
50mg | $ 374.00 | 0.0 | |
100mg | $ 713.00 | 0.0 | |
Exact Weight Packaging | $ 145.00 | 0.0 | |
Total | $ 0.0 |
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A112550
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Product Description
Catalogue Number | A112550 |
Chemical Name | ABT 737 |
Synonyms | 4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide; |
CAS Number | 852808-04-9 |
Molecular Formula | C₄₂H₄₅ClN₆O₅S₂ |
Appearance | Light Yellow to Yellow Solid |
Melting Point | 134-138°C (dec.) |
Molecular Weight | 813.43 |
Storage | -20°C |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | A selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines. Potent Bcl-2 Family inhibitor. |
References | Ikegaki, N., et al.: Cancer Res., 54, 6 |