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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1mg | $ 196.00 | 0.0 | |
| 5mg | $ 896.00 | 0.0 | |
| 10mg | $ 1642.00 | 0.0 | |
| 25mg | $ 3559.00 | 0.0 | |
| Exact Weight Packaging | $ 145.00 | 0.0 | |
| Total | $ 0.0 | ||
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A112432
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Product Description
| Catalogue Number | A112432 |
| Chemical Name | ABT-199-D10 |
| Synonyms | Venetoclax-d10 |
| Molecular Formula | C₄₅H₄₀D₁₀ClN₇O₇S |
| Molecular Weight | 878.5 |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | ABT-199-D10 is a deuterized form of ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
| References | Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013); |