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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 74.00 | 0.0 | |
| 10mg | $ 108.00 | 0.0 | |
| 50mg | $ 148.00 | 0.0 | |
| 100mg | $ 244.00 | 0.0 | |
| 500mg | $ 679.00 | 0.0 | |
| Exact Weight Packaging | $ 145.00 | 0.0 | |
| Total | $ 0.0 | ||
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A112430
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Product Description
| Catalogue Number | A112430 |
| Chemical Name | ABT 199 (Venetoclax) |
| Synonyms | 4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide; Venetoclax |
| CAS Number | 1257044-40-8 |
| Molecular Formula | C₄₅H₅₀ClN₇O₇S |
| Appearance | Light Yellow to Yellow Solid |
| Melting Point | 129-163ºC |
| Molecular Weight | 868.44 |
| Storage | -20°C |
| Solubility | Chloroform (Slightly, Heated), DMSO (Slightly, Heated) |
| Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
| References | Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013); |