A109045 Chemical Structure

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10mg
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mg50
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A109045

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Product Description

Catalogue NumberA109045
Chemical NameAbridin
Synonyms(22E)-26,27-Dinorcholesta-4,22-diene-3,24-dione;
CAS Number73030-56-5
Molecular FormulaC25H36O2
AppearanceWhite to Off-White Solid
Melting Point116-118°C
Molecular Weight368.55
Storage-20°C Freezer, Under inert atmosphere
SolubilityChloroform (Slightly), Methanol (Slightly, Sonicated)
Category Standards; Steroids;
ApplicationsAbridin is isolated from seed extracts of Abrus precatorius. Also, it is derived from Bisnorcholenaldehyde (B508830), which can be used to prepare 27-Nor-Δ4-dafachronic acid as a synthetic ligand of Caenorhabditis elegans DAF-12 receptor. It is also used to synthesize 3β,6α-dihydroxy-5α-cholan-23-one. Also, it is related to the parent compound Progesterone (P755900), which is a teroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer. This compound is a contaminant of emerging concern (CECs).
ReferencesSiddiqui, S., et al.: Pak. J. Sci. Ind. Res., 21, 158-161 (1978); Samaja, G., et al.: Bioorg. Med. Chem. Lett., 23, 2893 (2013); Nahar, L., et al.: Tetrahedron, 59, 8623 (2003); Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),