A108555 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 100.000.0
2.5mg
$ 220.000.0
mg5
$ 385.000.0
10mg
$ 730.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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A108555

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Product Description

Catalogue NumberA108555
Chemical Name3,5-cyclo-Abiraterone
Molecular FormulaC24H31NO
AppearanceWhite to Off-White Solid
Melting Point149-153°C
Molecular Weight349.51
StorageAmber Vial, -20°C Freezer, Under inert atmosphere
SolubilityChloroform (Slightly), DMSO (Slightly)
StabilityLight Sensitive
Category Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications3,5-cyclo-Abiraterone is derived from Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
ReferencesDenis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);