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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 2mg | $ 70.00 | 0.0 | |
| 5mg | $ 160.00 | 0.0 | |
| mg10 | $ 305.00 | 0.0 | |
| 25mg | $ 720.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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A108545
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Product Description
| Catalogue Number | A108545 |
| Chemical Name | (3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol |
| Synonyms | Abiraterone dimer |
| CAS Number | 186826-70-0 |
| Molecular Formula | C43H57NO2 |
| Molecular Weight | 619.92 |
| Category | Standards; Steroids; |
| Applications | (3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol is a derivative of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. |
| References | Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389 (2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005), |