A108530 Chemical Structure

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10mg
$ 200.000.0
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A108530

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Product Description

Catalogue NumberA108530
Chemical NameAbiraterone Isopropyl Ether
Synonyms3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
CAS Number2484719-15-3
Molecular FormulaC₂₇H₃₇NO
AppearanceWhite to Off-White Solid
Melting Point75-78°C
Molecular Weight391.59
Storage-20°C
SolubilityChloroform (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAbiraterone Isopropyl Ether is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17a-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
ReferencesDenis, L., et al.: Cancer, 72, 3888 (1993);