A108502 Chemical Structure

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A108502

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Product Description

Catalogue NumberA108502
Chemical NameAbiraterone Acetate-d4
Synonyms(3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Acetate-d4 (Ester); CB 7630-d4;
Alternate CAS #[154229-18-2] unlabelled
Molecular FormulaC26H29D4NO2
AppearanceWhite to Pale Yellow Solid
Melting Point133-135°C
Molecular Weight395.57
Storage-20°C Freezer
SolubilityMethanol (Slightly)
Category Standards; Steroids; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsLabelled Abiraterone acetate is a novel steroidal inhibitor of human Cytochrome P450(17α-Hydroxylase-C17,20-lyase): potential agent for the treatment of prostatic cancer.
ReferencesDenis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389 (2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),