A108485 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
5mg
$ 65.000.0
10mg
$ 100.000.0
25mg
$ 225.000.0
50mg
$ 410.000.0
100mg
$ 800.000.0
250mg
$ 1740.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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A108485

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Product Description

Catalogue NumberA108485
Chemical NameAbiraterone 3-((1-Chloroethyl)sulfinyl)benzene
Synonyms(8R,9S,10R,13S,14S)-3-(1-Chloro-1-(phenylsulfinyl)ethyl)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;
Molecular FormulaC₃₂H₃₈ClNO₂S
AppearanceBeige Solid
Molecular Weight536.17
SolubilityDichloromethane, Ethyl Acetate, Methanol
Category Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAbiraterone 3-((1-Chloroethyl)sulfinyl)benzene is an intermediate in synthesizing 3-Deoxy-3-acetylabiraterone-3-ene (D232060), which is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
ReferencesDenis, L., et al.: Cancer, 72, 3888 (1993);