Have a question about this product Click here.

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack Size Quantity Price (USD) Sub Total
1mg $ 80.00 0.0
2mg $ 150.00 0.0
2.5mg $ 175.00 0.0
5mg $ 315.00 0.0
10mg $ 567.00 0.0
25mg $ 1275.00 0.0
Exact Weight Packaging $ 75.00 / Vial 0.0
Total $ 0.0
Request another packsize ? Click here.

Inventory Status : Currently Back Ordered - Please Request Lead Time

Bulk Order Request for A105020

# Pack Size Unit Quantity
1.
2.
3.
4.
5.

Product Description

Catalogue Number: A105020
Chemical Name: Abacavir 5’-Phosphate
Synonyms: (1S,4R)- 4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Dihydrogen Phosphate (Ester); (1S-cis)-Abacavir Monophosphate; Abacavir - In House Impurity; Abacavir Impurities; Abacavir Metabolites
Impurity: Abacavir - In House Impurity
CAS Number: 136470-77-4
Molecular Formula: C₁₄H₁₉N₆O₄P
Appearance: White Solid
Melting Point: 189-194°C (dec.)
Molecular Weight: 366.31
Storage: -20˚C Freezer
Solubility: Methanol, Water
Category: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
References


Customers Also Viewed
Keywords: Buy 136470-77-4 | Purchase 136470-77-4 | Order 136470-77-4 | 136470-77-4 supplier | 136470-77-4 manufacturer | 136470-77-4 distributor | 136470-77-4 cost