Catalogue Number: A105015
Chemical Name: ent-Abacavir
Synonyms: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A; Abacavir Impurities; Ent-Abacavir
Impurity: Abacavir EP Impurity A
CAS Number: 136470-79-6
Molecular Formula: C₁₄H₁₈N₆O
Appearance: Off-White to Pale Yellow Solid
Melting Point: >77°C (dec.)
Molecular Weight: 286.33
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Category: Anti-virals, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: ent-Abacavir (Abacavir EP Impurity A) is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

All Products are stable to be shipped at room temperature, unless otherwise specified.
Product Rating
Keywords: Buy 136470-79-6 | Purchase 136470-79-6 | Order 136470-79-6 | 136470-79-6 supplier | 136470-79-6 manufacturer | 136470-79-6 distributor | 136470-79-6 cost

Order Product

  Pack size Price(USD)
1mg $95.00
25mg $1400.00
  Pack size Price(USD)
2.5mg $175.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Bulk Orders

If you require bulk orders or quantities you don't see listed, please click here

Translate »